Background and Objectives: Metabolic syndrome (MS) is a group of metabolic disorders, which its prevalence is growing worldwide and increases the risk of diabetes and cardiovascular diseases. In the present study, the metabolic syndrome status was investigated based on the NCEP/ATP III criteria in individuals at risk for diabetes.Methods: In this descriptive cross-sectional study, 514 individuals at risk of diabetes (20 to 60 years old), who referred to Amir-Al-Momenin Hospital of Ahvaz, entered the study based on inclusion and exclusion and using convenience sampling method. Data collection tools were demographic characteristics questionnaire, and anthropometric data entry checklist, systolic and diastolic blood pressure, and blood biomarkers (blood sugar, fasting blood sugar, triglyceride, etc.). In this study, MS was evaluated based on NCEP /ATP III criteria, which the presence of three or more than five criteria was indicative of the existence of this syndrome. Data analysis was performed using independent t-, Chi-square, and Pearson correlation tests at a significance level of 95%.Results: In this study, the most common ATP III criterion was abdominal obesity in patients at risk for diabetes. In general, 1.75% of statistical population had MS. Also, the prevalence of MS in women at risk for diabetes and non-employees was significantly higher. Also, there was a significant correlations between waist circumference and all the parameters, except FBS.Conclusion: The results of this study showed that the prevalence of MS in people at risk for diabetes is very high in the city of Ahvaz. Therefore, the risk of type II diabetes and cardiovascular diseases is very high in these individuals and requires serious corrective measures and special attention of health policy makers to this group.

Background: Metabolic syndrome (MS) is highly significant due to its association to type 2 diabetes and cardiovascular diseases. The purpose of this study was to compare the prevalence of MS according to the report of the Iranian National Committee of Obesity criteria (INCO) versus Adult Treatment Panel III (ATPIII) in Babol, North of Iran.Methods: Data obtained based on criteria ATP III from the Babol Lipid and Glucose Study (from July 2004 to September 2005) and were compared with the new INCO criteria 2010. The data were collected and analyzed.Results: In total, 933 adult males and females were evaluated. According to ATP III criteria, the overall prevalence of metabolic syndrome was 23.7% (95% confidence interval: 21%-26.4%); 28.4% and 9.4% were females and males, respectively; however, the prevalence was 20.5% (95% confidence interval: 17.9%-23.1%) according to the INCO criteria, 22.5% and 15.7% were females and males, respectively.Conclusion: The new INCO criteria for the metabolic syndrome proclaimed by the Iranian Committee of Obesity estimated a lower prevalence of syndrome in comparison with ATP III criteria in Babol.

Introduction: Metabolic syndrome (MS) is a risk factor for type 2 diabetes mellitus and cardiovascular disease. Limited information is available about the prevalence of the metabolic syndrome in rural areas of Iran.Materials and Methods: A total 1402 adults (1042 females and 360 males), aged between 18-90 yrs, participated in a community-based cross-sectional study. Prevalence of metabolic syndrome was determined by the definition of the National Cholestrol Education Program Adult Treatment Panel III (NCEP ATPIII), and results were compared with those based on the revised ATPIII and International Diabetes Federation (IDF) definitions.Results: Overall prevalence of ATP III defined metabolic syndrome was 25.6% compared to 29% and 33% using the revised ATP III, IDF definition respectively. The results of multiple logistic regression model showed after adjusting for age, sex, Body Mass Index (BMI), marital status, and education level, there was no difference between men and women for metabolic syndrome (P=0.2) by ATP III and revised ATP III definitions while prevalence of metabolic syndrome was 1.97 times greater in women versus men (95% CI: 1.4 - 2.7, p<0.001) by the IDF-definition. Sex-adjusted prevalence of metabolic syndrome (by three definitions) increased 1.05%, for each one year increase in age [95% CI: (1.04-1.06)]. In the current study, low serum High Density Lipoprotein Cholesterol (HDL-C) was the most common component of metabolic syndrome, while high fasting plasma glucose was the least common.Conclusion: These results show that the metabolic syndrome is prevalent in rural areas and interventional strategies should be considered for weight reduction and treating components of metabolic syndrome in this population.

Background and Aim: Metabolic Syndrome (MS) is a kind of metabolic disturbance generally coincident with abdominal obesity, hypertension, dyslipidemia and variation in glucose tolerance test .MS can be a prognostic parameter for fatal diseases such as cardiovascular diseases (CVD) and diabetes Mellitus. Different factors affect the prevalence of the disease.Materials and Methods: In this descriptive study, patients were selected according to ATP III (Adult Treatment Panel). The existence of at least three factors of the following was the criteria for affliction with the disease: (1) abdominal obesity with waist circumference  102 cm in men and ³88 cm in woman,  (2) hypertriglyceridemia ³150 mg/dL, (3) low high-density lipoprotein (HDL) cholesterol <40 mg/dL in men and <50 mg/dL in women, (4) blood pressure ³130/85 mmHg, (5) diabetic history and taking anti-glycemic drugs or having fasting blood sugar ≥110 mg/dL, (6) high blood pressure ³130/85 mmHg. The obtained data were statistically analyzed through SPSS software at the significant level P<0.05. Then, the frequency distribution of MS factors was determined with regard to age, sex, and habitation.Results: The age-adjusted prevalence of the MS was 25.4% and 21.7% in urban and rural area of Isfahan respectively. MS was higher among the women of Isfahan and central cities compared to men. Its highest frequency was seen in the eldery people (over 60) living in Isfahan villages (68.9%(Conclusion: It was found that approximately 21.9% of Iranian adults living in the central part of Iran suffer from MS. In summary, this study showed an increased risk of MS among middle-aged women in urbun areas which may be due to their insufficient physical activity.. The results indicate that the primary prevention should not only consider biological risk factors, but must also take socio-demographic conditions into account in order to identfy persons of high risk for diabetes and cardiovascular disease.

Introduction: Different results have been reported on the association between metabolic syndrome (MS) and cardiovascular diseases (CVD).The aim of this study is to determine the role of the Adult Treatment Cholesterol Program (ATP Ill) and International Diabetes Federation (IDF) definitions of metabolic syndrome in predicting CVD. Material and Methods: In this cohort study, all individuals aged over 40 yrs, phase I participants of the TLGS, with no histories of CVD were selected. Based on the APTIII and IDF criteria of the MS syndrome, they were divided into those with and those without the condition. All of the subjects were followed for a mean duration of 4.9±0.8 years for occurrence of CVD. The predictive ability of different definitions of the MS was evaluated in different regression models that included only the MS (model 1) and were also adjusted for age, sex, family history of premature CVD and smoking (model 2), serum LDL(model 3) and other components of the MS (model 4). Results: There were 3777 individuals' aged 54±10 years; 1536 (41%) where normal according to the both criteria of the MS and 1714 (45%) and 1900 (50%) subjects had MS according to the ATP III and IDF criteria respectively. New CVD occurred in 143 individuals (3.7%). In our study, the MS was the predictor of CVD in the first three models according to ATP III and IDF criteria; however, in model 4, none of the definitions of MS predicted CVD. After calculation of the area under the curve (AUC) for model 2 and 3, it was observed that the power of the ATP III criteria in model 2 for prediction of CVD was significantly higher than the IDF (AUC0.760 vs. 0.735, p<0.001) but no significant difference was observed between the 2 criteria in model 3. Conclusion: The ATP III and IDF definitions of the MS, it seems can similarly predict CVD after adjustment for the common CVD risk factors and LDL, whereas neither of the 2 definitions had this predictive power after adjustment of their components in addition to the earlier mentioned ones.

Background and Aim: Metabolic syndrome is considered as an important public health problem and there are few reports of this disease in the military, therefore, this study was performed to determine the prevalence of metabolic syndrome and its risk factors among the personnel of a military population. Methods: This descriptive cross-sectional study was conducted in 2021. In this study, 368 law enforcement personnel referred to the annual health monitoring plan, values of age, height, weight, body mass index (BMI), abdominal circumference, pelvic circumference, systolic pressure, diastolic pressure, fasting blood sugar, cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL) and alanine aminotransferase (ALT) were measured. Metabolic syndrome was calculated by two criteria, Adult Treatment Panel III (ATP III) and the International Diabetes Federation (IDF). Results: The mean age, weight, and BMI of the participants in this study were 39. 50 years, 83. 74 kg, and 27. 16 kg/m2, respectively. Abnormal levels of blood pressure, fasting blood sugar, triglycerides, cholesterol, HDL, LDL and ALT in individuals were 9. 2%, 16. 6%, 50. 5%, 4. 9%, 66. 6%, 1. 9% and 22. 6%, respectively. A high value of body mass index was observed in 83. 1% of people. The waist calculated values according to ATP III and IDF criteria were 7. 1% and 35. 9%, respectively. The prevalence of metabolic syndrome according to the ATP III and IDF criteria were 17. 7% and 20. 7%, respectively in the total population. There were positive corrections between metabolic syndrome with BMI and age. The prevalence of metabolic syndrome according to the ATP III and IDF criteria were 17. 7% and 19. 7% in the operational military unit, and 17. 6% and 21. 8% in the headquarters military unit, respectively. Conclusion: The results of the present study show that approximately one fifth of the studied military personnel have metabolic syndrome. Although this amount is less than the average of the society, considering the lifestyle and job of the military, and to achieve the high goals specified for this organization, the same amount needs attention. Therefore, the use of various educational methods to control weight and diet, as well as increase physical activity is recommended.

Introduction: The aim of the present study was to assess the diagnostic accuracy of the modified ATP III and IDF definitions of the metablic syndrome in identifying of insulin resistant individuals by HOMA_IR and to assess levels of agreement between these definitions and insulin resistance. Materials and Methods: The sample consisted of 347 nondiabetic subjects from the TLGS population (140 men and 207 women; aged 27-87 years). The reference standard for insulin resistance was determined by HOMA-IR and insulin resistance was defined as HOMA-IR≥2.5. Results: According to ATP III and IDF criteria 38.9%, 45% had metabolic syndrome respectively. The sensitivity and specificity of ATP III was 52.3% and 65% respectively, and this was 60% and 59% for IDF criteria respectively. Kappa agreement between modified ATP III and IDF with HOMA-IR was 0.14 and 0.15. Based on the area under the receiver operating characteristic curve constructed by counting metabolic syndrome components as recommended by modified ATP III and IDF diagnostic accuracy was fair. When each component of metabolic syndrome measures were considered as continous traits, waist circumference and fasting plasma glucose each separately had diagnostic accuracy equal or grater than at all the metabolic syndrome as a whole by ATP III and IDF criteria. Conclusion: ATP III and IDF definition, have low sensitivities for detecting insulin resistance and there is poor agreement between those criteria and insulin resistance. Measuring just waist circumference and fasting plasma glucose is simpler and may provide greater accuracy for identifying insulin resistance.

Introduction: This study amis at determining which components of the metabolic syndrome are the best predictors of its development. Material and Methods: In this cohort study, from the participants of the cross sectional phase of the Tehran Lipid and Glucose Study(TLGS), 2279 subjects (aged 20-87) who did not have the metabolic syndrome, based on modified ATP III criteria, and 2310 subjects (aged 20-87) without the metabolic syndrome according to IDF criteria were followed. Results: After a mean interval of 6.5 years, 462 and 602 new cases of the metabolic syndrome were diagnosed on basis of the modified ATP III and IDF criteria, respectively. The adjusted odds ratio for development of the metabolic syndrome by ATP III criteria was highest for central obesity in men, 2.8 (2.2-3.7) and for triglycerides in women, 2.8 (2.0-4.1). The adjusted odds ratio for development of the metabolic syndrome by IDF criteria was highest for triglycerides in both men and women, OR being: 2.8 (2.2-3.7) and 2.9 (1.9-4.3) respectively. The area under the ROC curves for waist circumference, triglycerides and HDL were the highest. A model that included waist circumference and triglycerides or waist circumference and HDL predicted the metabolic syndrome as well as a model that included all five metabolic syndrome components. Conclusion: High risk subjects should undergo periodic screening, including measurement of waist circumference, triglycerides and plasma HDL, for timely prediction of development of metabolic syndrome.